Looking for clinical studies or anecdotal case studies of adverse effects of replacement hormone therapy in women -- especially depession, irrational behavior, etc. Case in point is a 46 yo female who in a span of 40 days after initiating estrogen/progestin combination therapy left her job, left her husband and 3 children, and moved out of state. Individual is also taking Prozac (20 mg bid) but is likely underdosed. Previous diagnosis of mild clinical depression.
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