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View Full Version : Alzheimers & VPA


James Brody
October 28th, 2008, 11:33 AM
Is there an overlap between bipolar disorder and Alzheimers?

JimB

"Common Epilepsy Drug Could Prevent And Treat Alzheimer's Disease"

"ScienceDaily (Oct. 28, 2008) — Researchers at the University of British Columbia and Vancouver Coastal Health Research Institute have discovered that a drug used to treat epilepsy and bipolar disorders blocks the formation of plaques that cause Alzheimer's disease in animal mo The team led by UBC Psychiatry Prof. Weihong Song, who is also the Jack Brown and Family Professor and Chair in Alzheimer's Disease at UBC, found that if Valproic Acid (VPA) is used as a treatment in early stages of AD memory deficit is reversed.

"The study, published in the Journal of Experimental Medicine, reveals that VPA works by inhibiting the activity of an enzyme that produces a neurotoxic protein called beta Amyloid."

More at http://www.sciencedaily.com/releases/2008/10/081027101346.htm