James Brody
September 11th, 2008, 11:57 AM
And another example for classes in scientific method and experimental psychology. JB
"Immaturity Of The Brain May Cause Schizophrenia
"ScienceDaily (Sep. 11, 2008) — The underdevelopment of a specific region in the brain may lead to schizophrenia in individuals.
"Professor Tsuyoshi Miyakawa of Fujita Health University, National Institute for Physiological Sciences (NIPS), and Kyoto University led a research team in Japan, with support from the CREST program of Japan Science and Technology Agency (JST).
"First, the team investigated behaviors by conducting a systematic and well-defined behavioral test battery with alpha-CaMKII mutant mice, an animal model of schizophrenia. These mice showed abnormal behaviors similar to those of schizophrenic patients.
"Next, the team found the dentate gyrus neurons in hippocampus of the brain of these mice were not matured morphologically and physiologically. By a gene expression analysis, changes of gene expression related to the maturation of dentate gyrus neurons were also found in the brains of schizophrenic patients.
"Taken together, the immaturity of the dentate gyrus may be an underlying cause for schizophrenia."
More at http://www.sciencedaily.com/releases/2008/09/080910133341.htm
"Immaturity Of The Brain May Cause Schizophrenia
"ScienceDaily (Sep. 11, 2008) — The underdevelopment of a specific region in the brain may lead to schizophrenia in individuals.
"Professor Tsuyoshi Miyakawa of Fujita Health University, National Institute for Physiological Sciences (NIPS), and Kyoto University led a research team in Japan, with support from the CREST program of Japan Science and Technology Agency (JST).
"First, the team investigated behaviors by conducting a systematic and well-defined behavioral test battery with alpha-CaMKII mutant mice, an animal model of schizophrenia. These mice showed abnormal behaviors similar to those of schizophrenic patients.
"Next, the team found the dentate gyrus neurons in hippocampus of the brain of these mice were not matured morphologically and physiologically. By a gene expression analysis, changes of gene expression related to the maturation of dentate gyrus neurons were also found in the brains of schizophrenic patients.
"Taken together, the immaturity of the dentate gyrus may be an underlying cause for schizophrenia."
More at http://www.sciencedaily.com/releases/2008/09/080910133341.htm